# Analyze calibration data
# Libraries ----------
rm(list=ls())
library(dplyr)
##
## Attaching package: 'dplyr'
## The following objects are masked from 'package:stats':
##
## filter, lag
## The following objects are masked from 'package:base':
##
## intersect, setdiff, setequal, union
library(ggplot2)
library(network)
## network: Classes for Relational Data
## Version 1.15 created on 2019-04-01.
## copyright (c) 2005, Carter T. Butts, University of California-Irvine
## Mark S. Handcock, University of California -- Los Angeles
## David R. Hunter, Penn State University
## Martina Morris, University of Washington
## Skye Bender-deMoll, University of Washington
## For citation information, type citation("network").
## Type help("network-package") to get started.
library(networkDynamic)
##
## networkDynamic: version 0.10.0, created on 2019-04-04
## Copyright (c) 2019, Carter T. Butts, University of California -- Irvine
## Ayn Leslie-Cook, University of Washington
## Pavel N. Krivitsky, University of Wollongong
## Skye Bender-deMoll, University of Washington
## with contributions from
## Zack Almquist, University of California -- Irvine
## David R. Hunter, Penn State University
## Li Wang
## Kirk Li, University of Washington
## Steven M. Goodreau, University of Washington
## Jeffrey Horner
## Martina Morris, University of Washington
## Based on "statnet" project software (statnet.org).
## For license and citation information see statnet.org/attribution
## or type citation("networkDynamic").
# Read data and set meta-parameters ----------
#setwd('/project2/khanna7/bryanb/bc-navigation/nov*/bc*')
getwd()
## [1] "/project2/khanna7/bryanb/bc-navigation/nov30_fresh_git/bc-navigation/data-analysis"
N <- 5000
n.instances <- 30
run_length=180
control_list <- as.list(1:n.instances)
intervention_list <- as.list(1:n.instances)
noSocial_intervention_list <- as.list(1:n.instances)
dt_columns <- c(
#see `write.table` in https://github.com/khanna7/bc-navigation/blob/master/demography-reset.R for col names
"time",
"nintros", #deaths
"number.of.positive.bc.agents",
"number.of.hpos.agents",
"number.of.hneg.agents",
"number.of.diagnosed.cases",
"number.of.diagnostic.referrals",
"number.of.screening.referrals",
"number.of.screen.completed",
"number.of.dt.completed",
"number.of.symptomatic",
"number.of.navigated.agents",
"time.with.cancer",
"time.until.diagnosis",
"time.until.diagnosis.navigated",
"time.until.diagnosis.unnavigated",
"time.until.diagnosis.neigbor.navigated",
"number.of.diagnostic.referrals.at.t",
"number.of.screening.visits.at.t",#19
"number.of.ss0.diagnosed",#20
"number.of.ss1.diagnosed",#21
"number.of.ss2.diagnosed",#22
"number.of.ss3.diagnosed",#23
"number.of.ss0.diagnosed.navigated",#24
"number.of.ss1.diagnosed.navigated",#25
"number.of.ss2.diagnosed.navigated",#26
"number.of.ss3.diagnosed.navigated",#27
"number.of.ss0.diagnosed.unnavigated",#28
"number.of.ss1.diagnosed.unnavigated",#29
"number.of.ss2.diagnosed.unnavigated",#30
"number.of.ss3.diagnosed.unnavigated",#31
"number.of.ss0.diagnosed.neighbor_navigated", #32
"number.of.ss1.diagnosed.neighbor_navigated", #33
"number.of.ss2.diagnosed.neighbor_navigated", #34
"number.of.ss3.diagnosed.neighbor_navigated", #35
"number.of.bc.onsets", #36
"screening_referral_checker" #37
)
## Add names of data directories here
bc_navigation_root <- '/project2/khanna7/bryanb/bc-navigation/nov30_fresh_git/bc-navigation/'
date <- '11:53:08_2020-12-08'
full_run_name <- paste0(date, '_full_run/')
#control_name <- paste0(date, '_control/data/')
#intervention_name <- '14:15:09_2020-12-04_intervention/data/'
#intervention_no_social_name <- '14:15:09_2020-12-04_interventionNoSocial/data/'
#create lists
for (i in 1:n.instances){
control_list[[i]] <- read.table(paste0(bc_navigation_root, date, '_full_run/', date, '_control/data/', i,".data"))
}
for (i in 1:n.instances){
intervention_list[[i]] <- read.table(paste0(bc_navigation_root, date, '_full_run/', date,'_intervention/data/', i,".data"))
}
for (i in 1:n.instances){
noSocial_intervention_list[[i]] <- read.table(paste0(bc_navigation_root, date, '_full_run/', date, '_interventionNoSocial/data/', i,".data"))
}
#check whether the listed data is of the right length. Returns the instances that are missing data.
which(unlist(lapply(control_list, nrow) != run_length)) #number of months of the simulation
## integer(0)
which(unlist(lapply(intervention_list, nrow) != run_length))
## integer(0)
which(unlist(lapply(noSocial_intervention_list, nrow) != run_length))
## integer(0)
control.df <- bind_rows(control_list[1:n.instances])
intervention.df <- bind_rows(intervention_list[1:n.instances])
noSocial_intervention.df <- bind_rows(noSocial_intervention_list[1:n.instances])
colnames(control.df) <- dt_columns
colnames(intervention.df) <- dt_columns
colnames(noSocial_intervention.df) <- dt_columns
control.df$source <- rep(1:n.instances, each=run_length)
intervention.df$source <- rep(1:n.instances, each=run_length)
noSocial_intervention.df$source <- rep(1:n.instances, each=run_length)
# Compute incidence rate ----------
control.df <-
control.df %>%
mutate(number.of.bc.neg = N - number.of.positive.bc.agents)
intervention.df <-
intervention.df %>%
mutate(number.of.bc.neg = N - number.of.positive.bc.agents)
noSocial_intervention.df <-
noSocial_intervention.df %>%
mutate(number.of.bc.neg = N - number.of.positive.bc.agents)
# Compute means across variables at given time ----------
control.df_mean_at_time <-
control.df %>%
group_by(time) %>%
summarise(m_time.until.diagnosis = median(time.until.diagnosis),
m_number.of.navigated.agents = mean(number.of.navigated.agents),
m_number.of.screening.visits.at.t = mean(number.of.screening.visits.at.t),
m_number.of.positive.bc.agents = mean(number.of.positive.bc.agents),
m_number.of.diagnostic.referrals.at.t = mean(number.of.diagnostic.referrals.at.t),
m_number.of.screening.referrals = mean(number.of.screening.referrals),
m_number.of.dt.completed = mean(number.of.dt.completed),
m_number.of.screen.completed = mean(number.of.screen.completed),
m_number.of.hpos.agents = mean(number.of.hpos.agents),
m_number.of.hneg.agents = mean(number.of.hneg.agents),
m_number.of.diagnosed.cases = mean(number.of.diagnosed.cases),
m_number.of.positive.bc.agents = mean(number.of.positive.bc.agents),
m_nintros = mean(nintros)
)
intervention.df_mean_at_time <-
intervention.df %>%
group_by(time) %>%
summarise(m_time.until.diagnosis = median(time.until.diagnosis),
m_number.of.navigated.agents = mean(number.of.navigated.agents),
m_number.of.screening.visits.at.t = mean(number.of.screening.visits.at.t),
m_number.of.positive.bc.agents = mean(number.of.positive.bc.agents),
m_number.of.diagnostic.referrals.at.t = mean(number.of.diagnostic.referrals.at.t),
m_number.of.screening.referrals = mean(number.of.screening.referrals),
m_number.of.dt.completed = mean(number.of.dt.completed),
m_number.of.screen.completed = mean(number.of.screen.completed),
m_number.of.hpos.agents = mean(number.of.hpos.agents),
m_number.of.hneg.agents = mean(number.of.hneg.agents),
m_number.of.diagnosed.cases = mean(number.of.diagnosed.cases),
m_number.of.positive.bc.agents = mean(number.of.positive.bc.agents),
m_nintros = mean(nintros)
)
noSocial_intervention.df_mean_at_time <-
noSocial_intervention.df %>%
group_by(time) %>%
summarise(m_time.until.diagnosis = median(time.until.diagnosis),
m_number.of.navigated.agents = mean(number.of.navigated.agents),
m_number.of.screening.visits.at.t = mean(number.of.screening.visits.at.t),
m_number.of.positive.bc.agents = mean(number.of.positive.bc.agents),
m_number.of.diagnostic.referrals.at.t = mean(number.of.diagnostic.referrals.at.t),
m_number.of.screening.referrals = mean(number.of.screening.referrals),
m_number.of.dt.completed = mean(number.of.dt.completed),
m_number.of.screen.completed = mean(number.of.screen.completed),
m_number.of.hpos.agents = mean(number.of.hpos.agents),
m_number.of.hneg.agents = mean(number.of.hneg.agents),
m_number.of.diagnosed.cases = mean(number.of.diagnosed.cases),
m_number.of.positive.bc.agents = mean(number.of.positive.bc.agents),
m_nintros = mean(nintros)
)
# Plots ----------
#begin capturing output if you dont want to knit
#pdf(file='multiplot_out.pdf')
#may be used to color legend
colors <- c("control" = "green", "full intervention" = "blue", "no social" = "red")
#Time to diagnosis
ggplot()+
theme_bw()+
geom_line(data = control.df_mean_at_time, aes(x=time, y=m_time.until.diagnosis,color='green'))+
geom_line(data=control.df, alpha=0.1, aes(x=time, y=time.until.diagnosis,color='green'))+
geom_line(data = noSocial_intervention.df_mean_at_time, aes(x=time,y=m_time.until.diagnosis,color='red'))+
geom_line(data=noSocial_intervention.df, alpha=0.1, aes(x=time, y=time.until.diagnosis, color='red'))+
geom_line(data = intervention.df_mean_at_time, aes(x=time, y=m_time.until.diagnosis, color='blue'))+
geom_line(data=intervention.df, alpha=0.1, aes(x=time, y=time.until.diagnosis, color='blue'))#+

#scale_color_manual(
# values = c('blue', 'red', 'green'),
# labels = c("control", "Institutional with social", "Institutional without social")
#)
#Time from referral to testing (THIS WILL REQUIRE SUBSTANTIAL WORK: MODEL NEEDS TO RECORD TIME OF REFERRAL)
#Total number of navigated
ggplot()+
theme_bw()+
geom_line(data = control.df_mean_at_time, aes(x=time, y=m_number.of.navigated.agents, color='green'))+
geom_line(data=control.df, alpha=0.1, aes(x=time, y=number.of.navigated.agents, color='green'))+
geom_line(data = noSocial_intervention.df_mean_at_time, aes(x=time,y=m_number.of.navigated.agents, color='red'))+
geom_line(data=noSocial_intervention.df, alpha=0.1, aes(x=time, y=number.of.navigated.agents, color='red'))+
geom_line(data = intervention.df_mean_at_time, aes(x=time, y=m_number.of.navigated.agents, color='blue'))+
geom_line(data=intervention.df, alpha=0.1, aes(x=time, y=number.of.navigated.agents,color='blue'))#+

# scale_color_manual(
# values = c("green", "blue", "red"),
# labels = c("control", "Institutional with social", "Institutional without social")
#)
#number.of.positive.bc.agents
ggplot()+
theme_bw()+
geom_line(color='green', data = control.df_mean_at_time, aes(x=time, y=m_number.of.positive.bc.agents))+
geom_line(data=control.df, color='green', alpha=0.1, aes(x=time, y=number.of.positive.bc.agents))+
geom_line(color='red',data = noSocial_intervention.df_mean_at_time, aes(x=time, y=m_number.of.positive.bc.agents))+
geom_line(data=noSocial_intervention.df, color='red', alpha=0.1, aes(x=time, y=number.of.positive.bc.agents))+
geom_line(color='blue',data = intervention.df_mean_at_time, aes(x=time, y=m_number.of.positive.bc.agents))+
geom_line(data=intervention.df, color='blue', alpha=0.1, aes(x=time, y=number.of.positive.bc.agents))

#(number.of.positive.bc.agents/N)*100
#Breast Cancer Prevalence (%)
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green', alpha=0.1,aes(x=time, y=((number.of.positive.bc.agents/N)*100)))+
geom_line(data=control.df_mean_at_time, color='green', aes(x=time, y=((m_number.of.positive.bc.agents/N)*100)))+
geom_line(data=noSocial_intervention.df, color='red', alpha=0.1,aes(x=time, y=((number.of.positive.bc.agents/N)*100)))+
geom_line(data=noSocial_intervention.df_mean_at_time, color='red', aes(x=time, y=((m_number.of.positive.bc.agents/N)*100)))+
geom_line(data=intervention.df, color='blue', alpha=0.1,aes(x=time, y=((number.of.positive.bc.agents/N)*100)))+
geom_line(data=intervention.df_mean_at_time, color='blue', aes(x=time, y=((m_number.of.positive.bc.agents/N)*100)))+
ylim(c(0,5))+
labs(y="Breast Cancer Prevalence (%)")

#number.of.screening.visits.at.t
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.screening.visits.at.t))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.screening.visits.at.t))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.screening.visits.at.t))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.screening.visits.at.t))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.screening.visits.at.t))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.screening.visits.at.t))

#number.of.diagnostic.referrals.at.t
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.diagnostic.referrals.at.t))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.diagnostic.referrals.at.t))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.diagnostic.referrals.at.t))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.diagnostic.referrals.at.t))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.diagnostic.referrals.at.t))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.diagnostic.referrals.at.t))

#number.of.screening.referrals
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.screening.referrals))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.screening.referrals))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.screening.referrals))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.screening.referrals))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.screening.referrals))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.screening.referrals))

#number.of.diagnostic.referrals.at.t/number.of.screening.visits.at.t
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.diagnostic.referrals.at.t/number.of.screening.visits.at.t))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.diagnostic.referrals.at.t/m_number.of.screening.visits.at.t))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.diagnostic.referrals.at.t/number.of.screening.visits.at.t))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.diagnostic.referrals.at.t/m_number.of.screening.visits.at.t))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.diagnostic.referrals.at.t/number.of.screening.visits.at.t))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.diagnostic.referrals.at.t/m_number.of.screening.visits.at.t))+
ylim(c(0,0.5))

#number.of.dt.completed/number.of.screen.completed
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.dt.completed/number.of.screen.completed))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.dt.completed/m_number.of.screen.completed))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.dt.completed/number.of.screen.completed))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.dt.completed/m_number.of.screen.completed))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.dt.completed/number.of.screen.completed))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.dt.completed/m_number.of.screen.completed))

#number.of.screen.completed
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.screen.completed))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.screen.completed))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.screen.completed))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.screen.completed))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.screen.completed))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.screen.completed))

#number.of.dt.completed
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.dt.completed))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.dt.completed))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.dt.completed))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.dt.completed))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.dt.completed))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.dt.completed))

##Skipped for now
ggplot(control.df, aes(x=time))+
geom_line(aes(y=number.of.hpos.agents), alpha=0.1)+
geom_line(aes(y=number.of.hneg.agents), alpha=0.1)+
geom_line(aes(y=number.of.positive.bc.agents), alpha=0.1)+
theme_bw()+
geom_line(data = control.df_mean_at_time, aes(x=time, y=m_number.of.hpos.agents))+
geom_line(data = control.df_mean_at_time, aes(x=time, y=m_number.of.hneg.agents))+
geom_line(data = control.df_mean_at_time, aes(x=time, y=m_number.of.positive.bc.agents))+
ylim(c(0, 150))+
annotate(geom="text", x=625, y=112, label="All cases", col="black")+
annotate(geom="text", x=625, y=90, label="Hormone-positive", col="black")+
annotate(geom="text", x=625, y=30, label="Hormone-negative", col="black")+
labs(y="number")

#number.of.hneg.agents/number.of.hpos.agents
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.hneg.agents/number.of.hpos.agents))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.hneg.agents/m_number.of.hpos.agents))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.hneg.agents/number.of.hpos.agents))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.hneg.agents/m_number.of.hpos.agents))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.hneg.agents/number.of.hpos.agents))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.hneg.agents/m_number.of.hpos.agents))+
ylim(c(0,1))

#number.of.diagnosed.cases
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.diagnosed.cases))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.diagnosed.cases))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.diagnosed.cases))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.diagnosed.cases))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.diagnosed.cases))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.diagnosed.cases))

#number.of.positive.bc.agents
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=number.of.positive.bc.agents))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_number.of.positive.bc.agents))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=number.of.positive.bc.agents))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_number.of.positive.bc.agents))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=number.of.positive.bc.agents))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_number.of.positive.bc.agents))

#nintros
ggplot()+
theme_bw()+
geom_line(data=control.df, color='green',alpha=0.1, aes(x=time, y=nintros))+
geom_line(data=control.df_mean_at_time,color='green', aes(x=time, y=m_nintros))+
geom_line(data=noSocial_intervention.df, color='red',alpha=0.1, aes(x=time, y=nintros))+
geom_line(data=noSocial_intervention.df_mean_at_time,color='red', aes(x=time, y=m_nintros))+
geom_line(data=intervention.df, color='blue',alpha=0.1, aes(x=time, y=nintros))+
geom_line(data=intervention.df_mean_at_time,color='blue', aes(x=time, y=m_nintros))

#end capturing plots if not using knit
#dev.off()